.Pfizer Senior Scientist in Bothell, United States Why Patients Need YouPfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will AchieveThe ADC Chemistry (AC) group is seeking a highly motivated and creative synthetic chemist to develop novel payloads for antibody-drug conjugates (ADCs). You will apply organic synthesis and medicinal chemistry to development of new anticancer therapies. You will work collaboratively within the chemistry department and with researchers across the biology, computational, and translational sciences to advance oncology therapeutics from concept to clinic. As an ADC Chemist, you will drive projects and new ideas through drug design, implementation of the synthetic routes, and generating structure-activity relationships and hypotheses.How You Will Achieve ItUtilize experience and creativity in synthetic chemistry to advance ADC technologyExecute efficient routes for complex ADC payloads and drug linkersInterpret SAR and prioritize compounds for in vitro and in vivo biology assessmentContribute to and lead programs by executing lead optimization strategies and driving discovery goalsEffectively communicate and collaborate across a diverse research department to advance preclinical projectsPrepare patent applications and publish impactful researchWork cross-functionally with diverse teams to advance pre-clinical programsExpand the capabilities of chemistry department by implementing new techniques and molecular design and implement cutting-edge technologiesQualificationsMust-HavePh.D. degree in Organic/Medicinal Chemistry or related area of science ORM.S. degree in Organic/Medicinal Chemistry or related area of science with minimum 3 years related medicinal chemistry experience in the biopharmaceutical industry ORB.S. degree in Organic/Medicinal Chemistry or related area of science with minimum 5 years related medicinal chemistry experience in the biopharmaceutical industryContemporary knowledge of the key Medicinal Chemistry concepts and design tools required for pharmaceutical drug discoveryExcellent verbal and written communicationNice-to-HaveTrack record of accomplishment in chemical synthesis with examples of high impact publications from scientific work to datePHYSICAL/MENTAL REQUIREMENTSLift 10 lbsAdditional Information:Eligible for Employee ReferralLast Day to Apply: May 1, 2024The annual base salary for this position ranges from $88,300.00 to $147,100.00
