Your mission The Josep Carreras Leukaemia Research Institute (IJC) is a non-profit research institute based in Barcelona dedicated to advancing the understanding of leukemia and related disorders, in collaboration with the University of Barcelona and the Autonomous University of Barcelona. The IJC has laboratories in 5 clinical campuses: i) Hospital Clínic, ii) Hospital de Sant Pau and iii) Hospital Germans Trias Pujol iv) Hospital del Mar and v) Hospital Josep Trueta Girona. IJC serves as a collaborative center for basic researchers and physicians to work together on fundamental clinical and biological aspects of leukemia. The IJC offers an excellent work environment based on a multidisciplinary fusion of state-of-the-art ideas and facilities. Dr. Manel Esteller is the Director of the Josep Carreras Leukaemia Research Institute and the principal investigator of the Cancer Epigenetics Group, which is involved in the analysis of the type and mechanisms of epigenetic alterations in cancer cells, including aberrant changes in DNA methylation and histone modifications in cancer, study of the epigenetics machinery and associated mutations, and finally, testing of epigenetic drugs. Dr. Eva Musulén is a member of the Cancer Epigenetics Group with special interest in deep learning to identify new prognostic biomarkers in oncological diseases. We are looking for a junior postdoctoral researcher in the field of Cancer Diagnosis and Cancer Inmuno-Biology to join Dr. Esteller's Cancer Epigenetics Group in collaboration with Dr. Eva Musulén. The scientist will be responsible for the identification and validation of digital biomarkers and diagnostic tools for cancer detection, as well as new the identification of mechanisms of cancer progression disease and new treatments, with an additional focus on epigenetically regulated genes. The scientist should be able to process data obtained from diagnostic algorithmic tools and high-throughput screening methods such as whole slide images, whole DNA genome, methylome and transcriptome sequencing, CHIP-seq, MeDIP-seq, high-density methylation, expression arrays. The contract will be covered by MCIN/AEI/10.13039/501100011033 and European Union Next GenerationEU/PRTR (TED2021-131248B-I00 project). Your profile PhD in Biomedical Sciences or similar. Excellent track record of publications (first authorship in high-impact journals). Experience in the identification and validation of biomarkers and cancer diagnosis is required. Experience in epigenetic research and related digital bioinformatics analysis is an important plus. Experience in genome-wide CRISPR, drug screenings and deep learning is also an important plus. Experience in translational research is required. Good communication skills in English and can work independently. Motivation to achieve a high quality in your work. Why us? 5-month contract with the possibility of being extended. Full-time contract. Possible start date: 01/05/2024 The opportunity to contribute to cutting-edge research projects in Molecular Biology and Deep Learning approaches. Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute. The stimulating environment of the Barcelona metropolitan area. Competitive Salary to be further defined depending on candidate experience. The stimulating environment of the IJC and its scientific network. Deadline Please submit your application by 22/04/2024 About us What makes us different? Our mission is to investigate the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies through innovat ion to cure them. The vision of the Josep Carre ras Leukaemia Research Institute is to be a world-class reference and excellent research multicampus that contributes to the improvement of results, and the cure of patients affected by leukemia and other malignant hemopathies, through innovation, sustainability, social responsibility, talent, and professional experience. HR Excellence The European Commission awarded the IJC the HR Excellence seal in July 2019. The IJC continues to work to maintain its policies in line with the Charter and Code principles. This recognition reflects our commitment to continuously improving our human resources policies in line with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers. The HRS4R has the main objective of ensuring that research centers of excellence implement and respect the requirements of the European Charter for Researchers and the Code of Conduct for hiring researchers (from here on referred to as the Charter and Code) within their human resources policies. This EC initiative aims to promote training, professional development, and mobility for all European scientists. The IJC supports these values and principles, which will not only serve to strengthen its internal policies but will actively stimulate excellent research and firmly situate the organization as an institution with a stimulating working environment that favors the development of its scientists. IJC is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, and other legally protected characteristics
