MissionThe Almirall Research team in Barcelona is strengthening its core experimental department and is looking for a talented laboratory assistant with experience in in vivo Pharmacology. The team is enabling the small molecule and biologics pipeline from discovery up to preclinical development, and is co-responsible for delivery of high quality therapeutic drug candidates with a high potential for success in clinical development. Tasks and ResponsibilitiesKey responsibilities include but are not limited to: • Perform in vivo studies to answer scientific questions and to characterize MoA and efficacy of compounds including new drug candidates • Perform a variety of routine laboratory experiments and procedures, using state of the art laboratory equipment, recording and checking results for completeness and accuracy • Plan and initiate established and new experimental approaches with a high level of independence • Analyse and interpret experimental results and prepare reports/presentations • Assist team members in planning and execution of experiments • Work in a matrixed, fast paced highly collaborative environment with shared responsibilities • Effectively communicate within and across teams. • Carry out all laboratory activities in compliance with applicable regulations and protocols. • Conduct literature searches and reviews, compiling information for journals and suggest uses for new techniques to the team. • Maintain records of results and methodologies in electronic laboratory notebook. • Maintain equipment, lab area and supplies in a neat professional manner • Attend courses, lectures and conferences to further own knowledge on research and laboratory techniques, consulting with other researchers to exchange information. • Contribute to an enriching, positive and inclusive lab environment.Education Higher National Diploma in technical education (FP2) on sciences and at least 5 years of experience working in a biomedical research laboratory in the pharmacology field or Bs of science and at least 2 years of experience in a research lab. Specific Knowledge • EU license to work in procedures and projects on laboratory animal science or equivalent is a must • Proficiency in mouse handling and dosing (intradermal, intralesional, topical intraperitoneal, subcutaneous, intravenous, and oral gavage) • Ability to independently conduct tissue sample processing and analysis from rodents and/or minipigs using state of the art technologies. • Excellent aseptic cell culture technique for handling human and murine primary cells and transformed cell lines • Ideally experience in RT-PCR, ELISA, Flow Cytometry and Western Blot techniques. • Experience in state of the art immunology techniques to support isolation and ex vivo analysis of cells from animal tissues or human skin samples is a plus. • Strong attention to detail and analytical skills to resolve problems that require the use of basic scientific, mathematical, or technical principles. • Ability to communicate effectively both orally and in writing. • Proficiency in the use of software tools to support data analysis (e. g., Prism, FlowJo, Word, Excel, and Powerpoint) • Ability to critically interpret and effectively present data • Ability to take accountability and to prioritize work • Adaptabity to shifting priorities and changing work assignments • Ability to communicate in English is a plus Values• Care• Courage• Innovation• Simplicity
